氯化汞是一种非脂溶性物质,它不能通过血脑屏障(BBB),只有被直接注入血液循环中,而且其剂量高达足以损伤BBB时,才能进入脑组织。本研究采用大鼠腹腔注射氯化汞的方法,观察氯化汞对大鼠脑毛细管和突触小体的Na~+/K~+-ATP酶及Mg_4~(3+)-ATP酶活性的影响。实验采用体重150～200 g的Wistar大鼠,一次腹腔注射6 mg/kg体重的氯化汞。分 Mercuric chloride, a non-lipophilic substance, does not cross the blood-brain barrier (BBB) ​​and enters the brain only when it is infused directly into the bloodstream at doses high enough to damage the BBB. In this study, intraperitoneal injection of mercuric chloride in rats was used to observe the effects of mercuric chloride on the activity of Na ~ + / K ~ + -ATPase and Mg_4 ~ (3 +) - ATPase in the capillary and synaptosome of rat brain influences. Wistar rats with a body weight of 150-200 g were injected intraperitoneally with 6 mg / kg body weight of mercuric chloride. Minute