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局部5-氨基酮戊酸光动力疗法是利用光敏剂和光辐射治疗疾病的方法,目前多用于皮肤肿瘤、某些癌前病变和病毒疣等的治疗。皮肤真菌感染是一种常见病,由皮肤癣菌或念珠菌引起,使用标准抗真菌药物疗法治疗皮肤真菌感染,周期长,费用高,易出现耐药性;目前急需新的治疗方法。本文回顾了局部5-氨基酮戊酸光动力学疗法在体内、体外条件下对皮肤真菌感染的作用。
Local 5-aminolevulinic acid photodynamic therapy is the use of photosensitizers and light radiation treatment of diseases, currently used for skin tumors, some precancerous lesions and viral warts and other treatment. Skin fungal infection is a common disease caused by dermatophytes or Candida, use of standard antifungal therapy for fungal skin infections, long cycle, high cost, prone to drug resistance; the urgent need for new treatment. This article reviews the effects of topical 5-aminolevulinic acid photodynamic therapy on skin fungal infections in vitro and in vivo.