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由于广泛淋病奈瑟氏球菌对青霉素或四环素的耐药性,头孢三嗪被推荐用于临床,但只是肌肉注射,而Cefixime可供口服,吸收良好,单剂口服400mg或800mg血药水平超过MIC=0.125mg/L的时间可持续24h之久,对耐药淋病奈瑟氏球菌有极好活性。本文就Cefixime作为头孢三嗪代用品对耐药淋病奈瑟氏球菌活性在疗效、耐受性、安全性和敏感性等方面进行了比较。333例(男209例,女124例)无并发症的淋
Ceftriaxone is recommended for clinical use because of its resistance to penicillin or tetracycline due to extensive gonorrhea Neisseria gonorrhoeae but is administered intramuscularly only whereas Cefixime is available orally for good absorption with a single oral dose of 400 mg or 800 mg of blood above the MIC = 0.125mg / L for a long time lasting 24h, resistant Neisseria gonorrhoeae have excellent activity. In this paper Cefixime ceftriaxone as an alternative to drug-resistant Neisseria gonorrhoeae activity in the efficacy, tolerability, safety and sensitivity were compared. 333 cases (209 males and 124 females) without complications of the shower