论文部分内容阅读
目的:评价盐酸左氧氟沙星与痰热清注射液对心力衰竭患者伴肺部感染的疗效及其对机体氧化应激的影响。方法:选取2015年4月—2016年8月间收治的老年心力衰竭伴肺部感染患者84例,采用随机数字表法将其分为对照组和观察组,每组42例;对照组患者给予盐酸左氧氟沙星治疗,观察组患者对照组基础上加用痰热清注射液治疗,比较两组患者治疗后的疗效及机体氧化应激指标如超氧化物歧化酶(SOD)、丙二醛(MDA)、氧化低密度脂蛋白(ox-LDL)的变化。结果:观察组患者治疗后的总有效率为92.86%高于对照组为73.81%(P<0.05),SOD水平高于对照组(P<0.05),MDA、ox-LDL水平均低于对照组(P<0.05)。结论:采用盐酸左氧氟沙星与痰热清注射液联用治疗老年心力衰竭伴肺部感染患者,改善了SOD水平,降低了MDA、ox-LDL水平,能促进症状恢复,疗效较为确切。
Objective: To evaluate the curative effect of levofloxacin hydrochloride and Tanreqing injection on heart failure patients with pulmonary infection and its effect on oxidative stress. Methods: Eighty-four elderly patients with heart failure and pulmonary infection admitted from April 2015 to August 2016 were selected and randomly divided into control group and observation group, 42 cases in each group. The patients in control group were given Levofloxacin Hydrochloride was used to treat the patients in the observation group. The patients in the observation group were treated with Tanreqing Injection on the basis of the control group. The curative effect and the indicators of body oxidative stress such as superoxide dismutase (SOD), malondialdehyde (MDA) , Oxidized low-density lipoprotein (ox-LDL) changes. Results: The total effective rate of the observation group after treatment was 92.86% higher than that of the control group (73.81%, P <0.05), the level of SOD was higher than that of the control group (P <0.05), the levels of MDA and ox-LDL were lower (P <0.05). Conclusion: Levofloxacin hydrochloride combined with Tanreqing injection in elderly patients with heart failure and pulmonary infection can improve the level of SOD, reduce the levels of MDA and ox-LDL, and promote the recovery of symptoms.