论文部分内容阅读
取175只大鼠作实验,行小肠外置,并阻断上肠系膜血管75分钟诱发休克。然后注入白蛋白(ALB)10ml/kg和林格液(RL)44 ml/kg,可使血容量上升至休克前水平的80～90％,给与ALB(20 ml/kg),可使血容量上升至高于休克前水平。而未治疗休克组则出现血浓缩(Hct=58％),其血容量相当于休克前56％,而且动物于24 h内全部死亡。RL44ml/100g不能使血容量上升至休克前水平,24h存活率为32％。约占RL1/5的ALB剂量(10 ml/100g)时,24h存活率为46％,而当ALB剂量加大至20ml/100g时,血容量上升至休克前水平的115％,24h存活率为76％,高于小剂
Take 175 rats for experiments, the small intestine outside, and block the upper mesenteric vessels 75 minutes induced shock. Then, 10 ml / kg of albumin (ALB) and 44 ml / kg of Ringer’s solution (RL) were infused to raise the blood volume to 80-90% of the pre-shock level and to give ALB (20 ml / kg) The capacity rises above the pre-shock level. In the untreated shock group, however, blood concentration (Hct = 58%) appeared, with a blood volume equivalent to 56% of the shock before, and the animals all died within 24 h. RL44ml / 100g can not make blood volume increased to the level before shock, 24h survival rate of 32%. Survival rate was 46% at a ALB dose of about RL1 / 5 (10 ml / 100g), while blood volume increased to 115% of the pre shock level at a ALB dose of 20 ml / 100g. The 24h survival rate was 76%, higher than the small dose