依托咪酯注射液为静脉全麻药 ,现广泛用于临床。其部颁标准采用分光光度法测定含量 ,但由于注射液中加有丙二醇作助溶剂 ,影响测定结果。并且本品见光或储存过程中会产生降解反应 ,其降解产物也干扰分光测定。因此本文选择高效液相色谱法 ,以氨基比林为内标 ,测定本品的含量 , Etomidate injection for intravenous anesthetics, is now widely used in clinical. The ministerial standards using spectrophotometric determination of content, but due to the injection of propylene glycol as a solvent, affect the measurement results. And the product see light or storage process will have a degradation reaction, the degradation products also interfere with spectrophotometry. Therefore, this article selects high performance liquid chromatography, with aminopyrine as the internal standard, determination of the content of this product,