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树突状细胞(dendritic cell,DC)是体内功能最强的专业性抗原呈递细胞,近年来,DC在免疫应答中的双向调节作用引起了移植学者的广泛关注,其中耐受性树突状细胞(tolerogenicdendritic cells,tDCs)能够诱导特异性T细胞免疫耐受。由于DC主要分布在肝、心、肾等非淋巴器官,数量极为有
Dendritic cells (DCs) are the most potent specialized antigen-presenting cells in the body. In recent years, the bidirectional regulatory role of DCs in immune response has drawn the attention of transplant recipients. Among them, tolerogenic dendritic cells (tolerogenic dendritic cells, tDCs) can induce specific T cell immune tolerance. Because DC is mainly distributed in the liver, heart, kidney and other non-lymphoid organs, a very large number