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目的探讨准分子激光上皮瓣下角膜磨镶术(LASEK)后皮质类固醇性高眼压的发生情况及治疗结果。方法对行LASEK术的416眼术后滴用皮质类固醇(0.1%氟米龙)滴眼液4个月,观察眼压变化,对高眼压者给予治疗。结果18眼发生了皮质类固醇性高眼压,发生率为4.33%,经停用皮质类固醇滴眼液,给予0.5%噻吗心安滴眼液滴眼,仅1例加服醋甲唑胺,眼压均降至正常,视力完全恢复。结论术后定期随访,及时发现皮质类固醇性高眼压,治疗后不影响视力恢复。术前认真检查发现可疑病人,术后定期随访,有助于提高LASEK治疗近视的安全性。
Objective To investigate the occurrence and treatment of corticosteroid-induced ocular hypertension after excimer laser epithelial keratomileusis (LASEK). Methods 416 eyes of LASEK were treated with eye drops of corticosteroid (0.1% fluorometholone) for 4 months. The changes of intraocular pressure (IOP) were observed and the patients with high intraocular pressure were treated. Results Eighteen eyes developed corticosteroid-induced ocular hypertension with a rate of 4.33%. After stopping corticosteroid eye drops, they were given 0.5% timolol eye drops and only 1 case received methazolamide. Pressure dropped to normal, visual acuity fully restored. Conclusions Regular follow-up after surgery, and timely detection of corticosteroid high intraocular pressure, does not affect the visual acuity after treatment. Careful examination before surgery found suspicious patients, regular follow-up after surgery, help to improve the safety of LASEK treatment of myopia.