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目的:了解我院中药制剂致药品不良反应(ADR)发生的特点与一般规律。方法:对我院2004年1月～2009年6月收集到的中药制剂致136例ADR报告进行汇总分析。结果:引起ADR的中药制剂涉及38个品种。136例ADR中,41～70岁构成比最高,占71.32%;以静脉滴注给药途径引起的ADR最常见(占68.38%);ADR涉及的器官或系统主要为皮肤及其附件;绝大多数ADR转归良好。结论:中药制剂发生ADR与多种因素相关。临床在使用时应引起足够的重视,以减少ADR的发生。
Objective: To understand the characteristics and general rules of drug-induced adverse drug reaction (ADR) in our hospital. Methods: A total of 136 cases of ADR collected from our hospital from January 2004 to June 2009 were collected and analyzed. Results: The traditional Chinese medicine preparations that caused ADR involved 38 varieties. Among the 136 ADRs, the constituent ratio of 41 to 70 years old was the highest (71.32%). ADR caused by intravenous drip route was the most common (68.38%); the organ or system involved in ADR was mainly skin and its appendages; Most ADRs are good. Conclusion: The occurrence of ADR in TCM preparations is related to many factors. Clinical use should be given enough attention to reduce the incidence of ADR.