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高密度脂蛋白(HDL)具有抗动脉粥样硬化作用,血浆低水平HDL胆固醇(HDL-C)是冠心病的独立危险因素。通过药物、激素或生物疗法提高HDL-C水平,对于治疗脂质紊乱具有重要意义。该作者对血浆低水平HDL-C血症患者治疗的最新研究进展作一综述。
High-density lipoprotein (HDL) has anti-atherosclerotic effects and low plasma HDL cholesterol (HDL-C) is an independent risk factor for coronary heart disease. Increasing HDL-C levels with drugs, hormones or biological therapies is of great importance for the treatment of lipid disorders. The authors review recent progress in the treatment of patients with plasma low-grade HDL-C.