目的：阻塞性睡眠呼吸暂停综合征(OSAS)是一种以睡眠状态下反复发生呼吸暂停和(或)低通气为主要表现的并发多系统疾病的临床综合征。近年研究表明，OSAS与心肺系统疾病，脑血管疾病（CVD），情绪障碍和认知障碍，内分泌疾病的发生联系密切，其机制可能与OSAS导致的低氧血症、高碳酸血症、炎症、氧化应激、自主神经功能紊乱、血管内皮功能紊乱等有关。“,”Obstructive sleep apnea syndrome(OSAS)is characterized by repetitive apnea and/or hypopnea during sleep,and it can cause multisystem diseases.Recent researches have shown OSAS is closely correlated with heart and lung system diseases,cerebrovascular diseases, mood disorder and cognitive impairment,endocrine diseases.Its mechanisms may be related to hypoxemia,hypereapnia,inflammation,oxidative stress,and dysfunction of autonomic nerve and vascular endothelium caused by OSAS .