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神经干细胞具有强大的增殖能力和多分化潜能,其增殖与分化与生长因子、细胞因子、环境信号等因素密切相关。Notch信号途径可影响NSC的分化方向,核受体Nurrl等也参与了NSC的定向分化机制。
Neural stem cells have a strong proliferation and differentiation potential, proliferation and differentiation and growth factors, cytokines, environmental signals and other factors are closely related. Notch signaling pathway can affect the direction of NSC differentiation, nuclear receptors such as Nurrl also involved in the directional differentiation of NSC.