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目的探讨复方苦参注射液在晚期肿瘤患者化疗中的抗肿瘤作用和对肿瘤化疗的增效及减毒作用。方法将166例患者随机分为两组,治疗组(n=85)用化疗药物加复方苦参注射液,对照组(n=81)仅用化疗药物。结果治疗组和对照组的总有效率在统计学上有显著性差异(P<0.05);治疗组毒性反应低于对照组(P<0.05);在改善患者生活质量,提高免疫功能方面,两组比较均有显著性差异(P<0.05)。结论在化疗同时加用复方苦参注射液,能增强肿瘤患者机体免疫功能,增强化疗药物疗效,减少化疗药物不良反应。
Objective To investigate the anti-tumor effect of compound Kushen injection in the chemotherapy of patients with advanced cancer and the synergistic and attenuated effects on tumor chemotherapy. Methods One hundred and sixty-six patients were randomly divided into two groups. The treatment group (n = 85) received chemotherapy with Compound Kushen Injection and the control group (n = 81) with chemotherapy alone. Results The total effective rate of the treatment group and the control group was statistically significant difference (P <0.05); the toxicity of the treatment group was lower than that of the control group (P <0.05); in improving the quality of life of patients and improving the immune function, There was significant difference between the two groups (P <0.05). Conclusion Chemotherapy combined with compound Kushen injection can enhance immune function in cancer patients, enhance the efficacy of chemotherapy drugs and reduce the adverse reactions of chemotherapy drugs.