应用琼脂糖高压电泳和免疫固定技术，检测了洛阳地区健康汉族成人补体Ｂ因子的多态性。在１１９例无血缘关系个体中，Ｂｆ表型为ＳＳ７７人，ＦＳ３２人，ＦＦ１０人。计算出基因频率分别为ＢＦ＊Ｓ：０．７８１５，ＢＦ＊Ｆ：０．２１８５。与广东等南方汉族人的资料相比，其Ｂｆ遗传多态性分布有显著差异，对此进行了讨论。结果提供了具有地域特点的Ｂｆ多态性资料，可供医学等多方面的研究工作参考 The agarose high-pressure electrophoresis and immunofixation techniques were used to detect the polymorphism of complement B in healthy Han nationality in Luoyang. Among 119 unrelated individuals, the Bf phenotype was SS77, FS32, and FF10. Gene frequencies were calculated as BF * S: 0.7815, BF * F: 0.2185. The distribution of Bf genetic polymorphism was significantly different from that of southern Han population in Guangdong and so on. The results provide Bf polymorphism data with regional characteristics, which can be used for reference in many aspects of medical research