With a vast territory, the space-time distribution of water resources is uneven in China. There is a great difference in natural conditions and farmland management of agricultural production in different regions. The areal differentiation of agricultural products virtual water is obvious. Comparison with the agricultural products virtual water from 1995 to 2007 in China shows an increase in the first ten years and a little decrease in recent years. There has been a tendency of increase all the time in Northeast and Northwest, but a decrease after an increase firstly in other regions. The virtual water of food crops is the maximum which accounts for more than 70% in China, and that of vegetables is in a fust growth. The proportion of agricultural products virtual water to the total water resources in each region has a large difference, showing the imbalance of agricultural water in different regions, which accounts far 50%-90% in Northeast, and 125%-185% in North China. Under the guidance of virtual water strategy, based on the differences oj resource endowment, each region should adjust agricultural structure, decide production by water, and Select water suitable crops. In water-rich region, agricultural products of high water consumption should be planted appropriately, which will make full use of the abundant local water resources. In water-shortage region the crop production of high water consumption and low efficiency should be depressed, and that of low water consumption and high efficiency should be supported and increased. It will achieve reasonable disposition of water resources, promote ecological restoration and environmental protection, as well as ensure food security.