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目的：评价超选择性动脉内溶栓疗法（简称ＳＳＩＦ）对急性期或超急性期脑栓塞的疗效。材料与方法：１１例治疗前ＣＴ上未发现明确的低密度病灶，而所有病例脑血管造影均发现与症状一致的闭塞血管。使用Ｔｒａｃｋｅｒ－１８微导管，尽量使其先端通过栓子与血管壁之间的间隙到达栓子远端，然后注入纤溶剂进行溶栓。如不成功，则用微导管及导丝机械地将栓子部分捣碎后再行溶栓。结果：１２例中１１例完全或部分再开通，７例溶栓后症状改善，７例观察到颅内出血性变化。结论：ＳＳＩＦ局部纤溶剂浓度高，再开通率高，尿激酶用量少，并可减少栓子碎片向末梢移行的危险性，对急性期或超急性期脑栓塞是一种有效的治疗方法
Objective: To evaluate the efficacy of supra-selective intra-arterial thrombolysis (SSIF) in patients with acute or hyperacute cerebral embolism. MATERIALS AND METHODS: No definite low-density lesions were found in 11 cases of CT before treatment, and occluded vessels were found consistent with symptomatic findings in all cases of cerebral angiography. Using the Tracker-18 microcatheter, try to get the apex through the gap between the emboli and the vessel wall to the far end of the emboli, then inject fibrinolysis for thrombolysis. If unsuccessful, then with a microcatheter and guide wire mechanically broken pieces of emboli after thrombolysis. Results: Of the 12 cases, 11 cases were completely or partially reopened, the symptoms of 7 cases were improved after thrombolysis, and the intracranial hemorrhagic changes were observed in 7 cases. CONCLUSION: SSIF has high local fibrinolysis concentration, high reopening rate, less urokinase dosage, less risk of thrombus fragments moving to the distal end, and is an effective treatment for acute or hyperacute cerebral embolism