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目的 :在人群为基础的眼病调查中评价原发性开角型青光眼 (POAG)与近视的关系。方法 :调查北京市南部 3个自然村及 4个城区社区 4 0岁以上居民 4 4 5 1例。进行问卷及视力、屈光、倍频视野检查、非接触眼压测量、裂隙灯眼前节数码照相、晶状体后照明数码照相、散瞳眼底照相等检查。采用电脑验光结合插片法确定屈光状态。近视的定义为等效球镜度≤- 1 0D。近视又分为轻度近视及中、高度近视。根据存在典型的青光眼性视神经与视野改变、前房角开放诊断POAG。结果 :近视者与无近视者的POAG患病率分别为 3 31%、1 4 3% (校正性别与年龄的OR =2 16 ,P =0 0 0 1)。轻度近视者与中高度近视者POAG患病率分别为 2 4 6 %、4 4 9% (OR =0 5 0 9,P =0 0 74 )。与无近视者相比 ,轻度近视者POAG患病率校正性别、年龄因素的OR值为 1 5 2 (P =0 188) ;中高度近视者POAG患病率校正OR值为 3 17(P =0 0 0 0 )。 4 0～ 5 9岁组有、无近视者POAG患病率分别为 1 39%、0 5 6 % (OR =2 5 6 ,P =0 0 5 ) ;>6 0岁组有、无近视者POAG患病率分别为 5 72 %、2 77% (OR =2 0 4 ,P =0 0 0 8)。近视者的平均眼压较无近视者高 0 5 3mmHg(P =0 0 0 2 )。结论 :近视是POAG的重要危险因素。近视程度越高 ,年龄越大 ,POAG患?
OBJECTIVE: To evaluate the relationship between primary open angle glaucoma (POAG) and myopia in a population-based eye disease survey. Methods: To investigate 3 villages in the south of Beijing and 4 451 residents over the age of 4 in 4 urban communities. Questionnaire and visual acuity, refractive, octave visual field examination, non-contact intraocular pressure measurement, digital photography of slit lamp anterior segment, digital camera after lens, mydriatic fundus photography. Using computer optometry and insert method to determine refractive status. Myopia is defined as spherical equivalent ≤- 1 0D. Myopia is divided into mild myopia and high myopia. According to the presence of a typical glaucomatous optic nerve and visual field changes, anterior chamber angle diagnosis of POAG. Results: The prevalences of POAG in myopia and non-myopia were 31 31% and 14 3%, respectively (OR = 2 16, P = 0 0 01 for gender and age). The prevalences of POAG in mild myopia and moderate myopia were 24.6% and 44.9%, respectively (OR = 0. 059, P = 0.0074). Compared with those without myopia, the prevalence of POAG in mild myopia was corrected by sex and the OR value of age was 152 (P = 0 188). The OR of the POAG in middle and high myopia was 3 17 (P = 0 0 0 0). The prevalences of POAG in 40 ~ 59 years old group were 119% and 566%, respectively (OR = 256, P = 0 05); those with> 60 years old had no myopia The prevalences of POAG were 57.2% and 27.7%, respectively (OR = 2.044, P = 0.080). Myopia average intraocular pressure than those without myopia 0 5 3mmHg (P = 0.002). Conclusion: Myopia is an important risk factor for POAG. The higher the degree of myopia, the older, POAG suffering?