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360例T2DM患者,按ABI<0.9和≥0.9分为PAD组和非PAD组,观察ABI与各指标的相关性,对其进行统计分析。结果:PAD组在年龄、糖尿病病程、餐后2h血糖(2hPG)、糖化血红蛋白(HbA1c)、24h尿微量白蛋白(UAER)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、血肌酐(Cr)、C反应蛋白(CRP)水平方面均高于非PAD组,有统计学意义(P<0.05或P<0.01)。结论:ABI作为评估下肢血液循环不良或损伤的指标,具有无创、简便、价廉等优点。年龄大、病程长,血糖、血脂紊乱是加剧下肢动脉硬化过程的主要因素。
360 cases of T2DM patients were divided into PAD group and non-PAD group according to ABI <0.9 and ≥0.9. The correlation between ABI and each index was observed and statistically analyzed. Results: There were significant differences in age, duration of diabetes mellitus, 2hPG, HbA1c, UAER, TG, LDL-C, , Serum creatinine (Cr) and C-reactive protein (CRP) were significantly higher than those in non-PAD group (P <0.05 or P <0.01). Conclusion: ABI is an index to evaluate the poor circulation or injury of lower extremity. It has the advantages of noninvasive, simple and inexpensive. Age, long duration, blood glucose, dyslipidemia is to accelerate the process of lower extremity arteriosclerosis major factors.