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将2型糖尿病KK-Ay小鼠分为二甲双胍/高脂饮食、二甲双胍/低脂饮食、高脂饮食和低脂饮食4组,通过测定骨骼肌中腺苷酸活化蛋白激酶(AMPK)活性,发现二甲双胍和低脂饮食均可使AMPK活性增加,二者不存在累加效应。
Type 2 diabetic KK-Ay mice were divided into metformin / high-fat diet, metformin / low-fat diet, high-fat diet and low-fat diet 4 groups, by measuring the activity of adenosine-activated protein kinase (AMPK) Both metformin and low-fat diet can increase AMPK activity, there is no cumulative effect between the two.