【摘 要】
：
目的观察晚期胃癌非根治性术后腹腔注药联合静脉化疗和单纯静脉化疗的临床疗效。方法在广西兴安县人民医院进行晚期胃癌姑息性切除术的86例患者随机分成两组,每组43例,其中一
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目的观察晚期胃癌非根治性术后腹腔注药联合静脉化疗和单纯静脉化疗的临床疗效。方法在广西兴安县人民医院进行晚期胃癌姑息性切除术的86例患者随机分成两组,每组43例,其中一组患者单纯采用静脉化疗,称为对照组;另外一组患者采用腹腔注药联合静脉化疗,称为观察组。对比两组患者术后不良反应和生存率。结果两组患者术后不良反应主要有骨髓抑制、消化道反应、血红蛋白下降以及肝肾功能轻度异常等,但是两组差异比较没有统计学意义(P>0.05);观察组患者在手术后1、2、3年的生存率分别为83.7%、60.5%、44.2%,远远高于对照组的76.7%、30.2%、16.3%,两组差异比较具有统计学意义(P<0.05)。结论在晚期胃癌非根治性术后采用腹腔注药联合静脉化疗,有助于提高患者生存率,可在临床中推广使用。
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