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前哨淋巴结(SLN)是原发肿瘤淋巴引流区域内,肿瘤细胞发生转移时必经的第一站淋巴结。通过SLN活检可了解整个淋巴引流区域的肿瘤转移情况。许多小组的病例研究结果证实,SLN检测在外阴癌处理中有可行性与可信性;用于早期宫颈癌治疗初有成效,在子宫内膜癌研究中尚处于探索阶段。现就SLN检测在妇科恶性肿瘤中的研究进展作一综述。
Sentinel lymph nodes (SLNs) are the first lymph nodes in the area of lymphatic drainage of primary tumors that must pass through when tumor cells metastasize. SLN biopsy can understand the entire lymphatic drainage area of tumor metastasis. Many of the panel’s case studies confirm that SLN testing is feasible and reliable in the treatment of vulvar cancer; it has been initially effective in the treatment of early-stage cervical cancer and is still in its exploratory stage in the study of endometrial cancer. The progress of SLN detection in gynecological malignancies is reviewed.