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目的:观察四位一体联合术前访视模式治疗早期胃癌的临床疗效及其安全性。方法:将60例早期胃癌患者按随机数字表法分为治疗组和对照组,对照组予常规治疗和护理,治疗组在常规护理的基础上加用四位一体联合术前访视。结果:(1)治疗组总有效率为93.3%,对照组为70.0%,两组差异有统计学意义(P<0.05)。(2)治疗后治疗组中医证侯评分、SAS评分、SDS评分、QLQ-C30评分均明显优于对照组(P<0.05)。(3)治疗后治疗组CEA、CA72-4、CA19-9含量均明显低于对照组(P<0.05)。结论:四位一体联合术前访视模式能明显缓解早期胃癌患者的临床症状,改善患者焦虑抑郁状态,降低对患者生存质量的影响及血清中CEA、CA72-4、CA19-9水平。
Objective: To observe the clinical efficacy and safety of the combination of preoperative four-in-one model for early gastric cancer. Methods: Sixty patients with early gastric cancer were divided into treatment group and control group according to random number table. The control group was given conventional treatment and nursing. The treatment group was treated with conventional one and four-in-one combined with preoperative observation. Results: (1) The total effective rate was 93.3% in the treatment group and 70.0% in the control group, with significant difference between the two groups (P <0.05). (2) Houzheng score, SAS score, SDS score and QLQ-C30 score of the treatment group were significantly better than the control group after treatment (P <0.05). (3) After treatment, the levels of CEA, CA72-4 and CA19-9 in the treatment group were significantly lower than those in the control group (P <0.05). Conclusion: The combination of preoperative four-in-one preoperative model can significantly relieve the clinical symptoms of patients with early gastric cancer, improve anxiety and depression in patients, reduce the impact on quality of life and serum levels of CEA, CA72-4 and CA19-9.