论文部分内容阅读
目的了解甲型H1N1流感(甲流)疫苗接种后对甲流暴发疫情的影响。方法对2011年4—5月发生在学校的1起甲流暴发疫情进行流行病学描述性分析,用回顾性队列研究的方法分析甲流疫苗接种对该起暴发疫情的影响。结果该校542名师生中191人患病,罹患率为35.24%,发病时间主要集中在4月19—25日,发病人群主要为1～6年级的小学生(χ2=9.972,P<0.01),住校生发病高于非住校生,112名接种过甲流疫苗的师生发病率为16.96%,明显低于未接种疫苗的师生(40%),差异有统计学意义(χ2=20.661,P<0.05),OR=0.306(95%CI∶0.180～0.521)。结论接种甲流疫苗可以有效预防甲型H1N1流感的发生,减少暴发疫情的发病率。
Objective To understand the Influences of Influenza A (H1N1) influenza outbreak after Influenza A (H1N1) vaccination. Methods An Epidemiological Descriptive Analysis of 1 Outbreak of Influenza A in Schools from April to May in 2011 was conducted. The retrospective cohort study was conducted to analyze the impact of Influenza A vaccination on this outbreak. Results 191 of the 542 teachers and students in the school were sick and the attack rate was 35.24%. The onset time was mainly on April 19-25. The incidence of the disease was mainly from pupils in grades 1 to 6 (χ2 = 9.972, P <0.01) , The incidence of resident students was higher than that of non-resident students, the incidence rate of 112 teachers and students vaccinated with H1N1 vaccine was 16.96%, which was significantly lower than that of unvaccinated teachers and students (χ2 = 20.661, P <0.05), OR = 0.306 (95% CI: 180 ~ 0.521). Conclusion Influenza A vaccination can effectively prevent the occurrence of influenza A (H1N1) and reduce the incidence of outbreaks.