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目的:研究常规细胞遗传学在白血病造血干细胞移植方面的价值。方法:应用常规细胞遗传学方法定期检测白血病患者异基因造血干细胞移植前后常染色体、性染色体情况。结果:4例移植成功患者其中异性别3例性染色体表现为供者性染色体,原有异常消失;术后复发患者原有异常重现。结论:染色体可以作为异基因造血干细胞移植成功与否的标志和评价疗效的指标。
Objective: To study the value of routine cytogenetics in leukemia hematopoietic stem cell transplantation. Methods: The regular autosomal and sex chromosomes were detected by routine cytogenetics before and after allogeneic hematopoietic stem cell transplantation in patients with leukemia. Results: In 4 cases of transplanted patients, 3 cases of heterosexual chromosomes showed donor chromosomes, and the original abnormalities disappeared. The patients with recurrent cases were abnormally recovered. Conclusion: Chromosome can be used as a marker of successful allogeneic hematopoietic stem cell transplantation and evaluation of efficacy indicators.