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目的:探讨氯胺酮联合小剂量丙泊酚静脉麻醉在非气管插管下小儿麻醉中安全性和可靠性。方法:60例ASAⅠ或Ⅱ级择期手术患儿,随机均分为A、B 2组。A组静注氯胺酮1~2mɡ/+丙泊酚1~2mɡ/,B组单纯静注氯胺酮1~2mɡ/。全程面罩给氧,监测并记录麻醉诱导前(T0)、麻醉诱导后(T1)、切皮即刻(T2)、术毕即刻(T3)的SBP、DBP、MAP、HR、RR、SPO2,术中呼吸、循环抑制的发生率,患儿苏醒时间(自停麻药至完全清醒)和苏醒期躁动、恶心、呕吐的发生情况。结果:A组氯胺酮联合丙泊酚组麻醉效果好,苏醒快。无躁动、恶心、呕吐等症状发生,明显优于B组单纯静注氯胺酮组。结论:氯胺酮联合小剂量丙泊酚静脉麻醉在非气管插管下小儿麻醉中是有效的、安全可行的麻醉方法。
Objective: To investigate the safety and reliability of ketamine combined with low-dose propofol intravenous anesthesia in pediatric anesthesia without tracheal intubation. Methods: Sixty children with ASA Ⅰ or Ⅱ elective surgery were randomly divided into A and B 2 groups. A group of ketamine intravenous injection 1 ~ 2mɡ / + propofol 1 ~ 2mɡ / , B group simply intravenous ketamine 1 ~ 2mɡ / . The whole mask was oxygenated. SBP, DBP, MAP, HR, RR and SPO2 before anesthesia induction (T0), anesthesia induction (T1), incision immediately (T2) Respiration, the incidence of circulatory depression, the recovery time of the children (from the anesthesia until complete awake) and the onset of agitation, nausea and vomiting during the recovery phase. Results: A group of ketamine combined with propofol anesthesia effect is good, wake up fast. No restlessness, nausea, vomiting and other symptoms occurred, significantly better than the B group simple intravenous ketamine group. Conclusions: Ketamine combined with low-dose propofol intravenous anesthesia is an effective, safe and feasible method of anesthesia in pediatric anesthesia without tracheal intubation.