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目的研究烧伤患者病原菌的分布情况,并分析其耐药性。方法 145株烧伤患者的创面中经过培养共检测出的阳性菌株进行分离培养鉴定及药敏试验,对菌株分布特点及耐药性进行分析。结果 145株烧伤患者的创面中经过培养共检测出的阳性菌株,共24个菌种。检测出的菌株中铜绿假单胞菌占总菌株的35.2%,其次为金黄色葡萄球菌总菌株的11.7%。在药敏试验中发现,对铜绿假单胞菌耐药性最高的药物是左旋氧氟沙星,敏感性最高的药物为阿米卡星。产超广谱β-内酰胺酶的奇异变形杆菌和大肠埃细菌分别占70.0%和75.0%。结论本院烧伤感染细菌以铜绿假单胞菌和金黄色葡萄球菌为主,根据药敏试验结果选取合适的抗生素,对患者进行抗感染治疗,有利于患者创面的恢复。
Objective To study the distribution of pathogens in burn patients and to analyze their drug resistance. Methods A total of 145 burned patients were tested for their positive strains isolated from the wounds for identification and drug susceptibility testing. The distribution characteristics and drug resistance of the strains were analyzed. Results A total of 24 strains of positive strains were detected in the wounds of 145 burn patients. Pseudomonas aeruginosa detected in the strains accounted for 35.2% of the total strains, followed by Staphylococcus aureus total strains of 11.7%. In susceptibility testing, the drug most resistant to Pseudomonas aeruginosa was levofloxacin, the most sensitive drug being amikacin. Proteus mirabilis and Escherichia coli producing extended-spectrum β-lactamase accounted for 70.0% and 75.0%, respectively. CONCLUSIONS: Pseudomonas aeruginosa and Staphylococcus aureus are the main pathogenic bacteria in our hospital. According to the results of drug susceptibility test, antibiotics are selected to treat patients with anti-infective therapy, which is good for the recovery of wound surface.