大多数胶质母细胞瘤临床病程通常较短且进展迅速(原发性胶质母细胞瘤,IDH野生型),然而继发性胶质母细胞瘤由弥漫性星形细胞瘤或间变性星形细胞瘤进展而来,IDH突变是它的遗传学标志。胶质肉瘤和巨细胞型胶质母细胞瘤是胶质母细胞瘤罕见的组织学亚型,其进展迅速。本组检测36例胶质肉瘤和19例巨细胞型胶质母细胞瘤的遗传模式,所有36例胶质肉瘤和18例巨细胞型胶质母 Most glioblastomas have a generally short clinical course and rapid progression (primary glioblastoma, IDH wild type), whereas secondary glioblastoma consists of diffuse astrocytoma or anaplastic star Astrocytoma progresses, IDH mutations are its genetic markers. Gliosarcoma and giant cell glioblastoma are rare histological subtypes of glioblastoma that progress rapidly. This group of 36 cases of gliosarcoma and 19 cases of giant cell glioblastoma genetic model, all 36 cases of glioma and 18 cases of giant cell type gliosis