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目的探讨金边瑞香对荷S180瘤小鼠免疫功能的影响。方法MTT比色法测定小鼠T淋巴细胞增殖反应;鸡红细胞吞噬实验检测小鼠腹腔巨噬细胞吞噬功能,红细胞C3b受体花环(RBC-C3bRR)法检测小鼠红细胞免疫功能。结果20g/(kg.d),40 g/(kg.d)金边瑞香能提高荷S180瘤小鼠的T淋巴细胞增殖刺激指数、腹腔巨噬细胞的吞噬率和吞噬指数,20 g/(kg.d)金边瑞香可提高荷S180瘤小鼠的红细胞C3b受体花环结合率。结论金边瑞香对荷S180瘤小鼠的细胞免疫、非特异性免疫、红细胞免疫功能均有不同程度的促进作用。
Objective To investigate the effect of Phnom Penh on the immune function of mice bearing S180 tumor. Methods MTT colorimetric assay was used to detect the proliferation of mouse T lymphocytes. Chicken erythrocyte phagocytosis was used to detect the phagocytic function of mouse peritoneal macrophages. Red blood cell C3b receptor rosette (RBC-C3bRR) was used to detect the immune function of mouse erythrocytes. Results 20g/(kg.d) and 40 g/(kg.d) of Phnom Penh can increase the T lymphocyte proliferation stimulation index, phagocytosis rate and phagocytic index of peritoneal macrophages in mice bearing S180 tumor, 20 g/(kg). .d) Phnom Penh Ruixiang can increase the erythrocyte C3b receptor rosette binding rate in mice bearing S180 tumors. Conclusions Phnom Penh Ruixiang can promote the cellular immunity, non-specific immunity, and red blood cell immune function of mice bearing S180 tumor to varying degrees.