应用放射免疫法（ＲＩＡ）测定７１例肾小球疾病患儿尿中微量蛋白的含量。结果表明，微量蛋白尿的存在与肾功能状况密切相关。肾小球疾病常规尿蛋白定量、定性正常的病人中，尿中微量蛋白的持续增高常提示与激素依赖、频繁反复或复发有关，或为紫癜性肾炎、ＩｇＡ肾病的亚临床表现。微量蛋白尿的测定有助于判断肾小球疾病的病情、预后、疗效，为临床常规检查无蛋白尿的肾脏病患儿提供了一种诊断和随访的非创伤性方法。 Radioimmunoassay (RIA) was used to determine urinary microalbuminuria in 71 glomerular diseases. The results show that the presence of microalbuminuria and renal function are closely related. Glomerular diseases Conventional urinary protein, qualitative and normal patients, urinary micro-protein in the continuous increase often prompted with hormone dependence, frequent recurrence or relapse, or for purpura nephritis, subclinical manifestations of IgA nephropathy. The determination of microalbuminuria is helpful to judge the condition, prognosis and curative effect of glomerular disease, and provides a non-invasive method for diagnosis and follow-up of children with nephrotic disease without proteinuria.