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位于鼻粘膜,尤其是位于鼻粘膜上皮内、被豚草花粉特异性IgE致敏的肥大细胞数量的增加,是季节性变应性鼻炎发作的重要原因。作者研究了8名季节性变应性鼻炎病人鼻粘膜和鼻上皮中肥大细胞数量在不同季节的变化情况。8例病人中6女2男,平均32岁,均有5年以上典型的季节性变应性鼻炎的病史,皮肤变应原试验为阳性。于当年六月(上述病人的发病季节)、十月(发病季节过后)和次年一月(正值冬季,无花粉季节)分别从上述病人下鼻甲表面取下4mm~3的鼻粘膜标本,Carnoy氏液固定,酯酶染色。使用测面法测量标本,
Located in the nasal mucosa, especially located in the nasal epithelium, ragweed-specific IgE sensitized mast cells increased the number of seasonal allergic rhinitis is an important cause of the attack. The authors studied the changes of mast cells in nasal mucosa and nasal epithelium in eight patients with seasonal allergic rhinitis in different seasons. Eight of the 6 patients, 6 males and 2 females, averaged 32 years old, had a history of more than 5 years of typical seasonal allergic rhinitis and a skin allergen test was positive. Nasopharyngeal specimens of 4 mm to 3 were removed from the inferior turbinate surface of the patient in June of the same year (onset season of the above-mentioned patients), October (after onset of season), and January of the following year (positive winter, no pollen season) Carnoy’s fluid fixation, esterase staining. Using the measurement method to measure the specimen,