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探讨CA19-9动态变化在判断胰腺癌术后病人预后中的意义。方法:选择术前CA19-9显著升高的胰腺癌病例,对其CA19-9在术后进行动态检测并结合其临床表现和影像学结果,以判断CA19-9高低是否与肿瘤复发或转移有关。结果:术前CA19-9升高的胰腺癌病人,术后CA19-9均降至正常,但术后动态观察发现CA19-9出现再次升高者,其临床表现和影像学结果往往提示有肿瘤的复发或转移;而CA19-9稳定者则无肿瘤复发或转移的临床表现或影像学证据。结论:对于术前CA19-9升高的胰腺癌病人,术后降至正常而后又出现反跳者,往往提示胰腺癌术后有肿瘤复发或远处转移,CA19-9动态监测为临床判断胰腺癌综合治疗措施疗效的一个重要方法。
To investigate the dynamic changes of CA19-9 in the judgment of the prognosis of patients with pancreatic cancer. Methods: The cases of pancreatic cancer with significantly elevated preoperative CA19-9 were selected and their postoperative CA19-9 was dynamically detected. The clinical manifestations and imaging findings of CA19-9 were determined to determine whether CA19-9 was associated with tumor recurrence or metastasis . Results: Preoperative CA19-9 increased in patients with pancreatic cancer, CA19-9 after surgery were reduced to normal, but dynamic observation found CA19-9 increased again, the clinical manifestations and imaging findings often suggest that the tumor Recurrence or metastasis, whereas the CA19-9 stable had no clinical manifestations or imaging evidence of tumor recurrence or metastasis. Conclusion: For preoperative CA19-9 patients with elevated pancreatic cancer, after surgery to normal and then rebound, often prompted tumor recurrence or distant metastasis after surgery, CA19-9 dynamic monitoring of the clinical diagnosis of the pancreas Comprehensive treatment of cancer curative effect of an important method.