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目的探讨稽留流产常规药物流产时加用生化汤加味的临床疗效,并寻找更佳给药时间。方法将72例早期小稽留流产并住院治疗的患者随机分为3组。治疗1组于入院开始预处理时即同服生化汤加味方;治疗2组于米索前列醇用药当天开始服用中药生化汤加味方;对照组只用米非司酮联合米索前列醇药物流产。比较3组患者整体疗效、血清β-h CG、TNF-α变化。结果两治疗组总有效率高于对照组,差异有统计学意义(P<0.05)。两治疗组用药后TNF-α值均高于对照组,差异有统计学意义(P<0.05)。结论稽留流产常规药物流产时联合生化汤加味方治疗可显著增强药流效果,缩短阴道出血时间,减少患者清宫几率,且可使患者血清TNF-α值升高。
Objective To investigate the clinical efficacy of adding biochemical soup plus traditional abortion on missed abortion, and to find out the best time for administration. Methods Seventy-two patients with early abortion and hospitalization were randomly divided into three groups. Treatment group 1 was treated with Fuzhuanghuang Decoction at the time of pretreatment at the beginning of admission; treatment group 2 started to take traditional Chinese medicine Biochemical Decoction on the day of misoprostol treatment; and the control group only received mifepristone combined with misoprostol drug abortion. The overall efficacy, serum β-h CG and TNF-α in the three groups were compared. Results The total effective rate of the two treatment groups was higher than that of the control group, the difference was statistically significant (P <0.05). The TNF-α values of the two treatment groups were significantly higher than those of the control group (P <0.05). Conclusion Abortion abortion conventional abortion with biochemical Tonga decoction can significantly enhance the medical abortion effect, shorten the time of vaginal bleeding, reduce the chances of esophageal cancer, and patients with serum TNF-α increased.