对１７例冠心病（ＣＨＤ）和１５例高血压合并冠心病患者进行口服葡萄糖耐量试验，测定其血胰岛素（ＩＳ）和血糖水平，并与１０例健康人做对照。结果发现，ＣＨＤ和高血压合并冠心病患者都有胰岛素抵抗（ＩＲ），高胰岛素血症（ＨＩＳ）和部分糖耐量减低。高血压合并冠心病组ＩＲ和ＨＩＳ较ＣＨＤ组更为严重，且ＩＳ浓度呈持续增高状态。ＣＨＤ组血清总胆固醇与ＩＳ水平呈正相关，高血压合并冠心病组血清高密度脂蛋白胆固醇与ＩＳ水平呈显著负相关。 Oral glucose tolerance test was performed in 17 patients with coronary heart disease (CHD) and 15 patients with hypertension complicated with coronary heart disease. Blood insulin (IS) and blood glucose levels were measured and compared with 10 healthy subjects. The results showed that, CHD and hypertension patients with coronary heart disease have insulin resistance (IR), hyperinsulinemia (HIS) and some impaired glucose tolerance. Hypertension with coronary heart disease group IR and HIS more severe than the CHD group, and IS concentration was continuously increased. There was a positive correlation between serum total cholesterol and IS level in CHD group and a significant negative correlation between serum high density lipoprotein cholesterol and IS level in patients with hypertension and coronary heart disease.