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目的探讨糖尿病合并冠心病患者尿微量白蛋白/肌酐比值的变化及临床意义。方法选择我院收治的糖尿病合并冠心病患者124例为研究对象,按照冠心病严重程度分为A组、B组,A组为轻度冠心病者(60例),B组为冠心病较重者(64例),同期选择单纯糖尿病患者62例为C组,检测三组研究对象的尿微量白蛋白(UAlb)及与肌酐(UCr)比值。结果 C组患者尿微量白蛋白水平及其与尿肌酐比值均显著低于A、B两组,且A组均显著低于B组,差异均具有统计学意义(P<0.05)。结论糖尿病合并冠心病患者尿微量白蛋白/肌酐比值明显高于单纯糖尿病患者,且比值高低与冠心病严重程度紧密相关,可将该比值作为临床预测糖尿病合并冠心病指标之一,应予以重视。
Objective To investigate the changes of urinary albumin / creatinine ratio in diabetic patients with coronary heart disease and its clinical significance. Methods A total of 124 patients with diabetes mellitus and coronary heart disease admitted to our hospital were selected as study subjects. Patients were divided into group A and group B according to the severity of coronary heart disease. Group A was mild coronary heart disease (60 cases), group B was coronary heart disease (64 cases). Sixty-two patients with simple diabetes mellitus were selected as group C in the same period. Urinary microalbuminuria (UAb) and creatinine (UCr) ratio were measured in three groups. Results The urinary albumin level and urinary creatinine ratio in group C were significantly lower than those in group A and B, and the levels in group A were significantly lower than those in group B (P <0.05). Conclusions The urinary albumin / creatinine ratio in patients with diabetes mellitus and coronary heart disease is significantly higher than that in patients with simple diabetes mellitus, and the ratio is closely related to the severity of coronary heart disease. Therefore, this ratio should be taken as one of the indicators of clinically predicted diabetes mellitus with coronary heart disease.