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复方槐角口服液是在借鉴传统中成药槐角丸组方基础上研究开发的一种治疗痔疮的纯天然中药制剂。现经药理学研究证实,该口服液(5,10g·kg-1,ig)对由二甲苯诱发的小鼠耳部水肿和由蛋清诱发的大鼠足爪肿胀均呈现抑制作用,能有效地控制急性炎症过程,并且对棉球引起的大鼠肉芽肿组织增生也有一定抑制作用。在小鼠热板和扭体法实验模型上呈现镇痛作用。尚可缩短出血、凝血时间,止血效果明显。本研究结果提示该口服液仍能保持槐角丸重要药效学特性。
Compound Huaijiao oral solution is based on the traditional Chinese medicine Huaijiao pill group developed on the basis of a hemorrhoids treatment of natural Chinese medicine preparations. Pharmacological studies have confirmed that the oral solution (5,10 g · kg-1, ig) on xylene-induced mouse ear edema and egg-induced paw edema in rats were inhibited, effectively Control of acute inflammatory processes, and cotton balls caused by the proliferation of rat granuloma also have some inhibitory effect. In the mouse hot plate and writhing experimental model showed analgesic effect. Can still shorten the bleeding, coagulation time, hemostatic effect is obvious. The results of this study suggest that the oral liquid can still maintain Huaijiao Wan important pharmacodynamic properties.