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目的观察高强度聚焦超声(HIFU)治疗绝经前期功能失调性子宫出血(DUB)的临床疗效。方法选择2005年1月至2010年6月绝经过渡期DUB患者120例,随机分为治疗组和对照组,治疗组应用HIFU治疗机治疗,对照组使用常规刮宫术结合药物治疗,两组治疗前及治疗后3个月检测血常规,对患者月经量及月经期症状改善情况进行评定,定期随访。结果治疗组治愈51例,占85%,总有效率100%;对照组治愈14例,占23%,总有效率60%。治疗组治疗后血红蛋白增加量明显高于对照组(P<0.01)。结论 HIFU是治疗绝经过渡期DUB安全有效的微创治疗新方法,值得推广应用。
Objective To observe the clinical efficacy of high intensity focused ultrasound (HIFU) in the treatment of dysfunctional uterine bleeding (DUB) in premenopausal women. Methods One hundred and twenty patients with DUB at menopausal transitional period from January 2005 to June 2010 were randomly divided into treatment group and control group. HIFU treatment machine was used in the treatment group, and conventional curettage combined with drug treatment was used in the control group. And 3 months after the treatment of blood tests, the patient’s menstrual flow and menstrual symptoms were assessed, regular follow-up. Results The treatment group cured 51 cases, accounting for 85%, the total efficiency of 100%; control group, 14 cases were cured, accounting for 23%, the total efficiency of 60%. The increase of hemoglobin in the treatment group after treatment was significantly higher than that in the control group (P <0.01). Conclusion HIFU is a safe and effective new minimally invasive treatment for DUB during menopause. It is worth popularizing and applying.