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目的探讨常规降压药物联合抗焦虑药物治疗高血压合并焦虑症的临床疗效。方法选取巴彦淖尔市医院于2012—2013年收治的高血压合并焦虑症患者120例,随机分为试验组65例与对照组55例。试验组患者予以常规降压药物联合抗焦虑药物治疗,对照组给予常规降压药物治疗。比较两组患者治疗前后血压、汉密尔顿焦虑量表(HAMA)评分。结果治疗前两组患者收缩压和舒张压比较,差异无统计学意义(P>0.05)。治疗后试验组患者收缩压和舒张压低于对照组,差异有统计学意义(P<0.05)。两组患者治疗后收缩压和舒张压低于治疗前,差异有统计学意义(P<0.05)。治疗前两组患者HAMA评分比较,差异无统计学意义(P>0.05);治疗后试验组患者HAMA评分低于对照组,差异有统计学意义(P<0.05)。结论高血压合并焦虑症的患者在常规降压治疗的基础上联合抗焦虑药物治疗能有效控制血压,改善患者焦虑情绪。
Objective To investigate the clinical efficacy of conventional antihypertensive drugs combined with anti-anxiety drugs in the treatment of hypertension and anxiety. Methods A total of 120 patients with hypertension complicated with anxiety admitted in Bayannur Hospital from 2012 to 2013 were randomly divided into experimental group (65 cases) and control group (55 cases). Patients in the test group were given conventional antihypertensive drugs combined with anti-anxiety drugs, while those in the control group were given conventional antihypertensive drugs. Blood pressure and Hamilton Anxiety Scale (HAMA) scores were compared between the two groups before and after treatment. Results There was no significant difference in systolic and diastolic blood pressure between the two groups before treatment (P> 0.05). After treatment, the systolic and diastolic blood pressure of the experimental group was lower than that of the control group, with significant difference (P <0.05). The systolic and diastolic blood pressures were lower in both groups after treatment than before treatment (P <0.05). There was no significant difference in HAMA score between the two groups before treatment (P> 0.05). The HAMA score of the experimental group was lower than that of the control group after treatment (P <0.05). Conclusions Patients with hypertension and anxiety disorders can effectively control blood pressure and improve their anxiety by combining antihypertensive drugs with conventional antihypertensive treatment.