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目的:观察并分析香砂六君子汤配合雷贝拉唑在治疗胃溃疡方面的临床效果。方法:选取胃溃疡患者87例,将其随机分为两组,联合组患者(n=44)给予“香砂六君子汤+雷贝拉唑”进行联合治疗,对照组患者(n=43)给予常规治疗(包括雷贝拉唑+雷尼替丁+阿莫西林+维生素B1),两组患者均坚持治疗8周;对比分析两组患者的临床疗效。结果:①上腹痛缓解时间:联合组患者的上腹痛缓解时间为(2.9±0.7)d,对照组患者的上腹痛缓解时间为(3.6±0.6)d,联合组患者的上腹痛缓解时间要明显短于对照组,具有统计学意义(P<0.05)。②临床疗效:联合组患者治愈29例(65.91%,29/44),显效10例(22.73%,10/44),有效5例(11.36%,5/44),总有效44例(100%,44/44),对照组患者治愈12例(27.91%,12/43),显效18例(41.86%,18/43),有效8例(23.26%,10/43),总有效38例(88.37%,38/43);联合组患者的临床总有效率、治愈率均显著优于对照组(P<0.05)。结论:相对于单纯西药治疗,香砂六君子汤配合雷贝拉唑在治疗胃溃疡方面具有较好的临床效果,不仅病程短,而且治愈率高、复发率低,建议临床推广使用。
Objective: To observe and analyze the clinical effect of Xiangsha Liujunzi Decoction combined with rabeprazole in the treatment of gastric ulcer. Methods: Eighty-seven patients with gastric ulcer were selected and randomly divided into two groups. Patients in the combined group (n = 44) were treated with “Xiangsha Liujunzi Decoction plus Rabeprazole” 43) were given routine treatment (including rabeprazole + ranitidine + amoxicillin + vitamin B1), both groups insisted on treatment for 8 weeks; comparative analysis of two groups of patients with clinical efficacy. The pain relief time of the upper abdominal pain was (2.9 ± 0.7) d in the combined group and (3.6 ± 0.6) d in the control group. The relief time of the upper abdominal pain in the combined group was significant Shorter than the control group, with statistical significance (P <0.05). (2) Clinical efficacy: 29 cases (65.91%, 29/44) were cured in combination group, 10 cases were significantly effective (22.73%, 10/44), 5 cases were effective (11.36%, 5/44) , 44/44). The patients in the control group were cured in 12 cases (27.91%, 12/43), markedly effective in 18 cases (41.86%, 18/43), effective in 8 cases (23.26%, 10/43) 88.37%, 38/43). The total effective rate and the cure rate in the combination group were significantly better than those in the control group (P <0.05). Conclusion: Compared with pure western medicine, Xiangsha Liujunzi Decoction with rabeprazole has a good clinical effect in the treatment of gastric ulcer, not only short course, but also high cure rate and low recurrence rate, it is recommended for clinical use.