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软部肉瘤,依据组织型形成组织学的恶性度是反映预后的最重要因素之一。但是,由于软部肉瘤的发生率较低。还因为组织像具有多样性,有不少病例决定组织型的组织学恶性度时还存在着一些困难。因此寻求具备客观、重复性好的预后因素,对临床确有必要。作者自1962年以来,在大阪大学以软部肉瘤为对象总结了包括各种组织学因素与临床因素的经验。首先,以单一变量分析对预后因子进行讨论的项目有:性质、肿瘤的深度、肿瘤的部位、组织学的恶性度、细胞密度、分裂像、坏死程度作等了统计处理。其次考虑各因素间的相互影响,对单一因素有些还进行有目的的多变量分析。
Soft-tissue sarcoma, histologically based on the formation of histological malignancy is one of the most important factor to reflect the prognosis. However, due to the lower incidence of soft sarcoma. But also because of the diversity of the organization, there are still many difficulties in determining the degree of organizational histological malignancy. So seeking to have an objective, repeatable prognostic factors, the clinical really necessary. Since 1962, the author has summarized the experience of various soft tissue sarcomas including various histological factors and clinical factors at Osaka University. First, the single variable analysis of prognostic factors to discuss the project: the nature of the depth of the tumor, the tumor site, histological malignancy, cell density, mitotic image, the degree of necrosis for the statistical treatment. Second, consider the interaction between the various factors, some of the single factor also conducted purposeful multivariate analysis.