二尖瓣脱垂综合征(简称二脱),是二尖瓣单瓣或两个瓣在收缩中期或在全收缩期突入左房,引起胸痛,胸闷,心悸、气短、乏力等一系列临床表现。心脏听诊特征为心尖区闻及收缩期喀喇音(Systolic click),和/或收缩期杂音。近十五年来,国外报告颇多,随着超声心动图的广泛开展,国内也陆续有所报告。现把我院内科心血管组和超声心动图室从1978年10月以来发现11例,其中比较典型的4例报告如下,结合文献作一复习,并就二脱治疗问题提出探讨。临床资料一、年龄、性别、病程4例中,男女各2例,年龄15～43岁占3例,另1例67岁,病程1～29年。二、症状与体征4例中胸痛2例,多为隐痛,轻重不一,突然发生,痛的性质和部位不同于一般心绞痛,与劳累、紧张无关,含硝酸甘油不能缓解,持续时间不定,偶类 Mitral valve prolapse syndrome (referred to as two off), is the mitral valve or two petals in the middle of contraction or in the whole contraction into the left atrium, causing chest pain, chest tightness, palpitations, shortness of breath, fatigue and a series of clinical manifestations . Cardiac auscultation is characterized by apex area systolic clicks, and / or systolic murmur. Nearly fifteen years, many foreign reports, with the widespread echocardiography, the domestic one after another have been reported. Now we hospital internal medicine cardiovascular group and echocardiography room from October 1978 has found 11 cases, of which the more typical 4 cases are as follows, combined with a review of the literature, and discuss the problem of two off treatment. Clinical data A, age, gender, duration of 4 cases, 2 were male and female, aged 15 to 43 years in 3 cases, and the other 1 case 67 years old, duration of 1 to 29 years. Second, the symptoms and signs 4 cases of chest pain in 2 cases, mostly painful, severity varies suddenly occurs, the nature and location of pain is different from the general angina, and fatigue, tension has nothing to do with nitroglycerin can not be alleviated, the duration of indefinite, even class