干燥综合征又称 Sjogren 氏综合征,为慢性炎症性自身免疫性疾病。Sj(?)gren氏综合征患者常合并有肾脏损害,最常见者为间质性肾炎,临床表现为 Fanconi 综合征、肾小管酸中毒、肾性尿崩症、失钾性肌麻痹等。表现为肾小球肾炎者较少见。我院收治二例,例1表现为肾小球肾炎,二年内进展为终末期肾功能衰竭。例2表现为肾小管酸中毒,失钾性肌麻痹。现报告如下:例1 孙××,女,45岁,护士。病例号124548。因眼口干燥6年,水肿、高血压、蛋白尿二年于1983年8月11日入院。1977年初,患者自觉眼口干燥、关节疼痛、周身无力,毛发脱落而疑诊类风湿性关节炎,服强的松治疗后症状缓解。1981年发现高血压、双下肢轻度水肿,尿蛋白 Sjogren’s syndrome, also known as Sjogren’s syndrome, is a chronic inflammatory autoimmune disease. Sj (?) Gren’s syndrome patients often associated with kidney damage, the most common type of interstitial nephritis, clinical manifestations of Fanconi syndrome, renal tubular acidosis, nephrogenic diabetes insipidus, ametropic muscular paralysis and so on. Performance of glomerulonephritis are rare. Two cases admitted to our hospital, case 1 showed glomerulonephritis, two-year progress to end-stage renal failure. Example 2 showed renal tubular acidosis, ametropic muscular paralysis. Now report as follows: Example 1 Sun × ×, female, 45 years old, nurses. Case No. 124548. Due to dry eye for 6 years, edema, hypertension, proteinuria two years in August 11, 1983 admission. Early 1977, the patient conscious eye dry, joint pain, whole body weakness, hair loss and suspected rheumatoid arthritis, prednisone treatment of symptoms relieved. High blood pressure was found in 1981, mild edema in both lower extremities, and urinary protein