肝营养因子,即门脉因子,是指一些胰岛素及氨基酸等物质而言(表)。这些物质对于保持正常肝脏功能、防止肝的萎缩、调节肝的再生等均有重要作用,此外,对肝切除后的残存肝细胞与正常肝细胞的DNA合成有促进效果。十余年来对肝营养因子从基础到临床有许多工作者进行了大量的研究,今就有关这方面的研究成果加以综述。 Hepatic trophic factor, the portal factor, refers to some insulin and amino acids (Table). These substances play an important role in maintaining normal liver function, preventing the atrophy of the liver and regulating the regeneration of the liver. In addition, DNA synthesis of the remaining hepatocytes after liver resection and the normal liver cells are promoted. More than ten years of liver nutrition factors from basic to clinical many workers conducted a large number of studies, the research results in this regard are reviewed.