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目的探讨妊娠期血小板减少病因及治疗。方法对2000~2008年间本院50例妊娠期合并血小板减少患者的临床资料进行总结。结果妊娠期血小板减少的主要原因为妊娠期血小板减少症(GT)占62%(31/50);妊娠期高血压疾病引起血小板减少(PIH)占18%(9/50);特发性血少板性紫癜(ITP)占12%(6/50)。治疗以病因治疗为主,血小板计数>50×109/L,不予输注血小板治疗;血小板计数<50×109/L,积极使用糖皮质激素治疗;血小板计数<20×109/L,需使用糖皮质激素及血小板制剂。全部病例无孕产妇死亡。结论对妊娠期合并血小板减少以病因治疗为基础,针对血少板减少程度应用血小板制剂及糖皮质激素。
Objective To investigate the etiopathogenisis and treatment of thrombocytopenia during pregnancy. Methods The clinical data of 50 patients with thrombocytopenia during pregnancy in our hospital from 2000 to 2008 were summarized. Results The main reason of thrombocytopenia during pregnancy was 62% (31/50) of gestation thrombocytopenia (GT), 18% (9/50) of thrombocytopenia caused by hypertensive disorders in pregnancy, 9 cases of idiopathic blood Less purpura (ITP) accounted for 12% (6/50). Treatment of the main cause of treatment, platelet count> 50 × 109 / L, without infusion of platelet therapy; platelet count <50 × 109 / L, the active use of glucocorticoid therapy; platelet count <20 × 109 / L, the need to use Glucocorticoids and platelets. No maternal deaths were observed in all cases. Conclusions Gestational thrombocytopenia is based on etiological treatment and platelets and glucocorticoids are used for the reduction of thrombocytopenia.