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选用蒙克汀、橙油、舒胆通、三七皂甙提取母液组成几类单方及复方的溶石剂,对胆固醇型胆石及胆固醇和胆色素混合型的胆石进行了体外溶石实验.实验结果表明,蒙克汀及橙油对此二类胆石均为良好的溶石剂,胆石在此二种试剂中浸泡48h,减重率均在90%以上.两者相比,橙油的溶石效果更好.蒙克汀的效果是单方比复方乳剂好.舒胆通作为体外溶石剂效果不明显,混合使用时有增效作用.而三七皂甙提取母液则对胆石无溶解作用.
In this study, the chelating agents such as monkshine, orange oil, schrenia, and notoginseng saponin were used to form several types of single and complex solutions of the petrolatum. The in vitro dissolution experiments were performed on the gallstone-type gallstones and the gallstone mixed with cholesterol and porphyrin. The experimental results show that both monkeptine and orange oil are good dissolvers for these two types of gallstones, and gallstone is soaked in these two reagents for 48 hours with the weight loss rates above 90%. Compared with the two, orange oil has a better effect of dissolving limestone. Monocetin’s effect is unilateral better than the compound emulsion. Shu Dan Tong as in vitro dissolution of the effect is not obvious, when mixed with synergistic effect. The notoginseng saponin extraction mother liquor is insoluble on the role of gallstone.