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目的:研究癫癎患者生活质量特点及其影响因素。方法:采用病例-对照、问卷调查的方法进行评估分析。结果:成人与儿童癫癎患者生活质量显著下降(P<0.001),成人和儿童分别以社会功能(患者55.6±31.3,正常对照87.0±22.6)和社会支持(患者34.6±29.1,正常对照70.7±27.4)的损害最为严重。成人患者焦虑与抑郁的得分显著高于对照组(P<0.01)。药物不良反应和社会心理学评分水平与生活质量多个方面独立相关。结论:癫癎患者生活质量受损,以社会功能/社会支持损害最为严重。社会心理学和药物不良反应比疾病本身对生活质量的影响更大。
Objective: To study the quality of life of epileptic patients and its influencing factors. Methods: The case-control, questionnaire survey method for evaluation analysis. Results: The quality of life of adults and children with epilepsy was significantly decreased (P <0.001). The scores of social function (55.6 ± 31.3 in patients and 87.0 ± 22.6 in normal controls) and social support (34.6 ± 29.1 in patients and 70.7 ± 27.4) is most severely damaged. The scores of anxiety and depression in adult patients were significantly higher than those in the control group (P <0.01). Adverse drug reactions and psychosocial scores were independently associated with multiple aspects of quality of life. Conclusion: The quality of life of epilepsy patients is impaired, with the most serious damage being social function / social support. Social psychology and adverse drug reactions have a greater impact on quality of life than the disease itself.