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目的:评价自拟中药煎剂与更昔洛韦眼用凝胶联用对患者头面眼部带状疱疹抗病毒的临床疗效。方法:选取2009年5月—2014年6月期间诊治的带状疱疹患者68例临床资料,将其随机分为观察组(35例)和对照组(33例);对照组患者给予更昔洛韦眼用凝胶外用治疗,观察组患者在对照组基础上加用自拟中药煎剂外用治疗,比较两组患者用药后的总有效率和带状疱疹创面基本愈合情况。结果:观察组患者用药后的总有效率为100.00%高于对照组为84.85%(P<0.05),疱疹消肿时间、疼痛消失时间和创面结痂时间均优于对照组(P<0.05)。结论:自拟中药煎剂与更昔洛韦眼用凝胶联用治疗患者头面眼部带状疱疹,具有消肿止痛、控制眼部感染扩散的抗病毒疗效较显著,用药安全性高。
OBJECTIVE: To evaluate the clinical efficacy of self-made traditional Chinese medicine decoction combined with ganciclovir ophthalmic gel in the treatment of head herpes zoster antivirus in patients. Methods: The clinical data of 68 patients with herpes zoster diagnosed and treated during the period from May 2009 to June 2014 were selected and randomly divided into observation group (35 cases) and control group (33 cases). Patients in the control group were given ganciclovir Wei eye gel with external treatment, the observation group patients in the control group based on the use of self-made decoction of traditional Chinese medicine treatment, the two groups were compared the total effective rate and the basic healing of shingles wounds. Results: The total effective rate in the observation group was 100.00% higher than that in the control group (84.85%, P <0.05), and the herpes swelling time, disappearance time and wound scab time were all better than those in the control group (P <0.05) . Conclusion: The combination of Chinese medicine decoction and ganciclovir ophthalmic gel in the treatment of ocular herpes zoster in patients with head swelling, relieving pain and controlling the spread of ophthalmic infection has obvious curative effect of anti-virus and high medication safety.