论文部分内容阅读
目的:观察分析肠道病毒71型(EV71)感染所致重症手足口病患儿临床表现及循环障碍发生的特点及治疗方法。方法:回顾性分析186例重症手足口病患儿为研究对象,其中EV71感染者53例,柯萨奇病毒A组16型(COA16)感染者97例,其他病毒感染者36例,根据感染病毒不同分为EV71组、CA16组、其他病毒组,观察三组患儿循环障碍发生等临床特点、治疗方法及预后。结果:EV 71组患儿循环障碍、神经系统受累、肺出血临床发生率高于CA16组及其他病毒组,EV71组中心动过速、血压增高、末端循环障碍为EV71组最为常见的循环障碍临床表现,且发生率高于CA16组及其他病毒组,EV71组住院时间长于CA16组及其他病毒组,差异均有统计学意义(P<0.05)。结论:EV71感染重症手足口病患儿神经系统受损、肺出血、循环障碍发生率高于其他病毒感染,血压不稳、心率加快是其主要循环障碍临床表现,有效的预防措施能够有效的防止EV71感染患儿短时间内发展为危重病例。
Objective: To observe and analyze the clinical manifestations and the characteristics and treatment of circulatory disorders in children with severe hand-foot-mouth disease caused by enterovirus 71 (EV71) infection. Methods: 186 children with severe HFMD were retrospectively analyzed. Among them, 53 were EV71, 97 were coxsackievirus A (COA16), and 36 were other viruses. According to the infection of virus Different divided into EV71 group, CA16 group, other virus group, observed three groups of children with circulatory disorders such as clinical features, treatment and prognosis. Results: The incidence of circulatory disturbance, nervous system involvement and pulmonary hemorrhage in EV 71 group was significantly higher than that in CA16 group and other viruses. The EVDA group had higher tachycardia, increased blood pressure, and terminal circulation disorder was the most common circulatory disturbance in EV71 group (P <0.05). The hospitalization time in EV71 group was longer than that in CA16 group and other virus groups, the difference was statistically significant (P <0.05). CONCLUSIONS: EV71 is associated with impaired nervous system, pulmonary hemorrhage and circulatory disturbance in children with severe HFMD. The incidence of circulatory disorders is higher than that of other virus infections. The unstable blood pressure and fast heart rate are the main clinical manifestations of circulatory disturbance. Effective preventive measures can effectively prevent EV71 infection in children with short-term development of critical cases.