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持续性室速病人单服奎尼丁治疗经程序电刺激(PES)证实失败后,用奎尼丁加美西律联合治疗的效果,目前尚有争议。作者前瞻性地观察了20例这类病人,目的在于确定联合用药后不再诱发室速的病例有多少。 方法 入选者20例,年龄从35岁到77岁。在停用所有抗心律失常药物至少5个半衰期后行基础电生理检查。三根电极导管分别置于高位右房、希氏束、右室心尖,行心腔内
Continuous ventricular tachycardia patients with single-serving quinidine treatment by program electrical stimulation (PES) proved to be unsuccessful, the effect of combined treatment with quinidine and mexile-permeation, is currently controversial. The authors prospectively looked at 20 such patients in order to determine the number of cases that no longer induce VT after the combination. Methods 20 patients were enrolled in the study, ranging in age from 35 to 77 years old. Basic electrophysiological examination was performed after discontinuation of all antiarrhythmic drugs for at least 5 half-lives. Three lead catheters were placed in the high right atrium, His bundle, right apex apical, intracardiac line