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藻酸双酯钠(多糖硫酸酯,PSS)为青岛第三制药厂生产,属酸性粘多糖,类肝素药物。国内广泛用于防治缺血性心、脑血管疾病。现将我们遇到2例该药所致的过敏性休克报道如下。 例1,男性,55yr,因发作性头痛,头晕10余年,加重伴左侧肢体酸麻无力、口角流涎20d入院。平时血压波动于17.3-20/12-14.6kPa(130-150/90-110mmHg)之间,有低分子右旋糖酐及磺胺药过敏史。查体:血压18.6/14.6kPa(140/110mmHg),眼睑无浮肿,结膜无充血;双肺呼吸音
Sodium alginate (polysaccharide sulfate, PSS) for the third pharmaceutical factory in Qingdao, is an acid mucopolysaccharide, heparin-like drugs. Domestic widely used in the prevention and treatment of ischemic heart and cerebrovascular disease. Now we encounter two cases of allergic shock caused by the drug reported below. Example 1, male, 55yr, due to episodes of headache, dizziness for more than 10 years, aggravating with the left limb tingling, mouth drool 20d admission. Usually fluctuations in blood pressure between 17.3-20 / 12-14.6kPa (130-150 / 90-110mmHg), with low molecular weight dextran and sulfa drug allergy history. Examination: blood pressure 18.6 / 14.6kPa (140 / 110mmHg), edema without edema, conjunctival hyperemia; lung breath sounds