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纳络酮 (naloxone,NX)为羟 (二 )氢酮衍生物 ,结构与吗啡相似 ,是吗啡受体的特异性拮抗药 ,易通过血脑屏障 ,可防止并取代吗啡样物质与受体结合 ,解除中枢抑制作用 ,对休克、呼吸功能不全、双肺复苏等各种中毒等疗效确切。笔者仅就其在精神神经科的应用作一综述。1
Naloxone (NX) is a hydro xenobiotic derivative with a similar structure to morphine and is a specific antagonist of morphine receptors. It is easy to cross the blood-brain barrier to prevent and replace the binding of morphine-like substances to receptors , Relieve the central inhibitory effect on shock, respiratory insufficiency, lung resuscitation and other poisoning and other curative effect is exact. I only make an overview of its application in neurology. 1